Genome Sequence of the Bacteriocin-Producing Strain Lactococcus garvieae DCC43

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Genome sequence of the bacteriocin-producing strain Lactococcus garvieae DCC43.

This work describes the draft genome sequence of Lactococcus garvieae DCC43. The 2.2-Mb draft genome contains 2,227 predicted protein-coding genes, among which is a region encoding the bacteriocin garvicin ML. No antibiotic resistance genes or capsule-related virulence genes were identified. Two plasmid replication regions indicate that this strain likely contains plasmids. Comparative genomics...

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Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis.

Garvicin ML (GarML) is a circular bacteriocin produced by Lactococcus garvieae DCC43. The recently published draft genome of this strain allowed determination of the genetic background for bacteriocin production. Bioinformatic analysis identified a gene cluster consisting of nine open reading frames likely involved in the production of and immunity to GarML. The garA gene encodes the bacterioci...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2012

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.01864-12